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Uticaria - Doctors NO help! No Cause - Ideas??

Hello,

So posting this for my brother who is a 25 year old active male with no past medical history except for what I am about to describe.  Family history is negative for "rashes", autoimmune disease - pretty much every disease except self-induced diabetes (eating to the point of 400 pounds), heart attack in the 70s and pneumonia - typical occurrences in late life.  My brother as a teenager developed Uticaria - large, raised, red and itchy bumps overnight for no reason.  It is relieved by Benadryl.  Initially it was scary because it spread all over his ENTIRE body (including face and the soles of his feet).  At some point, he went to the ER, they ran a drug panel (NOTHING) and  got an inject of a steroid and was prescribed Prednisone for 2 weeks I believe (it has been a while).  Rash disappeared.  In the mean time (we're in Canada so things take FOREVER to happen - yay healthcare!), he had an allergist and a dermatologist appointment.  Allergist found nothing and the dermatologist just walked in "you have nothing to show me" and walked out.  As you know, we can't just summon the rash to appear, otherwise we would not need a dermatologist if we knew the trigger.

Now at 25 (so at least 7 years later).  It came back in late February (it is May now) and it has come back viciously!  It's over 3 months - chronic and won't go away.  Normally 6 weeks is what you would expect.  Cetirzine, Loratadine and Benadryl used to work.  The first two stopped working now.  The latter provides SOME relief - but does not eliminate the rash. However, my brother just can't keep taking antihistamines forever!  The rash also now is starting to HURT him on occasion.  He chooses not to go to the ER as the wait time in Canada is 6 hours.  We PCP set out for an "urgent" dermatologist and allergist consult - that was 2 MONTHS ago (we called to make sure he faxed the order AGAIN).  This time we too pictures so the arrogant doctor won't just walk out after 1 hour of us waiting for him in the waiting room.  He did go to urgent care and got an epi shot - it felt "cold" (naturally) after the shot and protected him for over a day.  He got a script of prednisone - however the dosages for prednisone from the PCP vs urgent care MD are VERY different, he is unsure which to take and is hoping to get his allergist appointment before he fills one of the scripts.  He gets his rash now daily and it gets worse at the end of the day (night time).

We tried:
-Isolating the cats and himself (he is not allergic to them anyway... but JUST in case it happened after having them for 10 years+++)
-Professionally getting air duct cleaned
-Professionally getting carpet cleaned
-Changed laundry detergent to baby detergent without any "harmful chemicals"
-We changed the curtains
-Had our house professionally cleaned in addition to the air duct/carpet
-RE-Cleaned every piece of fabric (clothing, furniture etc).
-Changed his mattress
-Had him not wear any clothes from home (he was in his scrubs the entire day - yes without socks and underwear)
-Changed the shampoo to baby shampoo
-Starved him for a day (no food)
-Let him eat food prepared in other places (not home incase we're using triggers)
-Cut fish, nuts, tomatoes, the common offenders etc
-Cold showers don't work
-He does NOT itch them
-No drugs - he's not on any prescription drugs, non-prescription drugs, herbals, supplements, OTC etc.  He has been tested at LEAST three times for "bad drugs" - twice by the PCP and once at the ER (last one two weeks ago).  For his work, he was also clean.

Absolutely nothing worked.  It just pops out daily - pretty much the moment benadryl stops working (out of your system), BOOM rash time.  I'm thinking of getting his PCP to get a blood test for cortisol/thyroid levels - but their rash looks nothing like what he gets.  Again he gets the typical Uticaria - LARGE, raised, botchy and red rash (no oozing, pustules etc) - warm to the touch and itchy - sometimes painful.  Location: EVERYTHING - including face, near eyes (above), feet neck, soles of feet, etc.  Happens mostly at night or after a nap a lot.

Sure we can symptomatically relief him with Benadryl if he wants to spend the rest of his life sleeping.......  and maybe use topical creams - but that doesn't relief the rash just the itching.

Since doctors (and believe me I would know - I work in the medical field) go for the most common offender - drugs, illicit drugs, food, etc (or charge $15 on this site per question and provide the most common answers as I browsed through this forum) - I'm hoping that maybe someone here has heard of something like this and can provide insight

ANY help/insight... anything is appreciate.... the smallest suggestions can lead to great/bright ideas!
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Avatar universal
Hi. I have had chronic urticaria on both legs every day since 2006. I too have autoimmunes (15 diseases to be exact). The itching drives me crazy and I haven't been able to wear shorts in years. The only things that help are my daily antihistamines (zyrtec or claritin) and clobetesol .05%, a prescripton steroid ointment.  The ointment thins the skin if used too thick or too often. So, I save it for my unbearable days, and it helps almost immediately. Hope my story is useful to you.
Helpful - 0
1530171 tn?1448129593
Hi MzTeachtx.

It's likely a... this is going to be a long word : Psychoneuroimmunoendocrinology field case- a new field in medicine coined from Psychoneuroimmunology- which studies the psyche,( the mind with its contents) interacting with the nervous system with the involvement of the endocrine & the immune system, as part of the whole body response.

To my opinion, the treatment which is worth exploring, before going into a medical wild goose chase, is through Energy Medicine.
Look into NAET (Dr. Nambudripad's Allergy Elimination Techniques) trained Doctors or Practitioners. NAET is a breakthrough treatment for allergies.
I have worked in this area using another similar method, called Allergy Antidotes.

You may want to research this further on your own and please get back to me, either by posting again or by pm and I can give you more details.
I have personally used a specific release procedure in 2 cases similar to your brother's resulting in  complete remission, however, results may vary from person to person.

Note that my comments and suggestions are only for educational purposes and are not intended as a substitute for medical advice.

Take care.
Niko
Helpful - 0
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