850029 tn?1238857820


Does anyone know if you can grow resistant to antihistamines?  I've been on Zyrtec for a year and feel like it doesn't work as well as it used to.  I know that I have more allergens around me but would think I still should be getting relief.  I spend at least $100 a month trying to get some relief.  I'm thinking with nothing working I should just save myself $100:)  the only time I feel someone what better is taking Advil Cold and Sinus, the Zyrtec seems to do nothing......  Any advice?
4 Responses
746512 tn?1388807580
Try some different OTC antihistamines, they may help too.  

Your body doesn't grow resistant to the medicine, however over repeat exposures, your response to the allergen will increase.  This increase in response will cause you to need a higher dose of the same medication to get the same level of relief.  

Try and avoid the allergens all together or look into allergy shots which treats allergies at the immune response level.  
Avatar universal
i use 2 types of antihistamine for hayfever, i use them on alternative years - i find if i use the same one for 2 summers it does not work for the for the 3rd summer - but by alternating them i am fine.
Avatar universal
I think you might. I've also been on zyrtec for a while and it seems to be less effective than it used to be... My sinus problems aren't that bad now though...although when my sinus problems fell off, my skin started acting up with hives and all. sigh.
850029 tn?1238857820
Have you switched to a different antihistamine?  I thought about doubling my dosage but that will cost me $60 a month on top of the nasal sprays etc.  My doctor put me on it last year when I started breaking out in hives all over.  I realized I had the fragrance allergy.   I can control the fragrance part of it but had chronic sinus infections due to my other allergies after I took myself off it.  I do nasal rinses, take nasal spray and try to minimize the allergens around me and it really feels like the Zyrtec doesn't little.   And its not even spring allergy time in Minnesota!!!!!
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