I would consider asking your wife's physician about lyme disease (if you guys have it in Fiji), Chronic Fatigue Syndrome and/or fibromyalgia.
How are you?
The features that you mentioned can be due to SLE (systemic lupus erythematosus). Lupus is a condition characterized by chronic inflammation of body tissues caused by autoimmune disease. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE). Both discoid and systemic lupus are more common in women than men.
Common complaints and symptoms include fatigue, low-grade fever, loss of appetite, muscle aches, arthritis, ulcers of the mouth and nose, facial rash ("butterfly rash") and photosensitivity to light.
Diagnosis is made by physical examination, blood tests, ESR, ANA testing, direct analysis of internal body fluids, and tissue biopsies.
There is no permanent cure for SLE.Treatment is to relieve the symptoms.
If you are suspecting allergy to alcohol or cold weather, you can get it diagnosed by skin ***** or patch tests from a qualified dermatologist. For cold urticaria, place an ice cube on the patient's forearm for 4 minutes and observe the area for 10 minutes afterwards. If the patient has cold urticaria, the area will become itchy and then swell approximately 2 minutes after removing the ice cube.
Another possibility from these symptoms is Gaucher’s disease which is an inherited metabolic disorder that leads to the accumulation of a particular fatty substance throughout the body. Diagnosis is by a bone marrow biopsy or specific blood tests.
So, pls consult a physician for a confirmatory diagnosis as treatment will depend on the same.
Take care and God bless.