If I remember right, elevated globulins (IgQ, IgG, IgM & IgE) can be seen in people who have liver problems, inflammatory diseases (lupus, RA), chronic infections and myelomas.
Immunoglobulin A (IgA) is an antibody playing a critical role in mucosal immunity. More IgA is produced in mucosal linings than all other types of antibody combined. In its secretory form, is the main immunoglobulin found in mucous secretions, including tears, saliva, colostrum, intestinal juice, vaginal fluid and secretions from the prostate and respiratory epithelium. It is also found in small amounts in blood. Because it is resistant to degradation by enzymes, secretory IgA can survive in harsh environments such as the digestive and respiratory tracts, to provide protection against microbes that multiply in body secretions.
Hope this answered your query. In case you need more information you can go to : http://en.wikipedia.org/wiki/IgA.
My son has allergies and asthma. Recently we had a test done for Immunoglobulin levels. His level of IgA was very high - 360. What does this mean?