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Can the compound Allicin from crushed garlic be used to fight Candida Auris?

Are compounds like curcumin and allicin being studied on pan-resistant fungus like Candida Auris?
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Avatar universal
I'm not sure that circumin has very strong anti-fungal or antibiotic properties.  It does have some antibacterial effect, and some believe this is why it was first used in food prep in the first place, but it isn't the strongest thing out there.  Garlic does have antibiotic and anti-fungal properties, but what is used is raw garlic oil or juice, not isolated allicin, which isn't very stable to use by itself in the open air.  The real issue here, though, is getting whatever you're using to where the infection is in a strength strong enough to not only kill the fungus but also kill it's offspring or it comes right back again.  With the fungus you're concerned about, these things like candida are omnipresent, we all have some, but we all don't get sick from them.  The one you're concerned about appears to have developed drug resistance, but that's mostly a big problem when the infection is so pervasive it gets into internal organs.  If you're immune system is strong enough, that doesn't happen, but the drugs used to kill this stuff also kills of a lot of the immune system and that's how so many of these things have become so dangerous, and also because antibiotics have been so overused, including in food animals mostly to make them grow faster and to market faster, that we now have super bugs.  They adapt.  So if you could get the garlic to where the infection is for a long enough period of time it might at the least weaken the fungus, but that's much harder in internal organs than when they are on the skin or near the open air.  Lots of things kill this stuff -- hydrogen peroxide, bleach, vinegar are all probably stronger than garlic, but again, are also toxic inside the body.  A stronger plant anti-fungal is oregano oil, and there are many others as well.  It's possible a good stew of these substances might work, but drugs were invented because plants are not as strong or work as quickly.  I'm sure research has been done, but in order to afford to do pure plant research requires a lot of money and with no ability to patent the result you can't make that money back and our medical system and our research system is mostly driven by the promise of great wealth.  That means that even when research is done, the studies are small and not conclusive, and the best studies aren't trying to determine if garlic would work but rather whether a drug mimicking how garlic works can be developed.  I'm also not sure allicin is the reason garlic has antibiotic qualities -- it's probably a combination of substances working together, in garlic's case sulphur based compounds.  Now, to find out if it is being studied, you need to go to PubMed and see if there are any studies, and I'm betting there are, but I'm also betting they're not great studies because of the financing problem.  To truly answer your question would require actual testing on animals or patients, and that's very very expensive.  What happens in test tube doesn't necessarily translate to a complicated human.  
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