4 Supplements That Will Help You Live Longer
Co-enzyme Q10, Idebenone, The Carnitines and Alpha-Lipoic Acid.
Supplement No. 1: Co-enzyme Q10
(CoQ10) Benefits Creates energy that allows all cells in human body to function
Serves as powerful antioxidant Fights atherosclerosis (hardening of the arteries)
Removes dangerous excess iron, helping to prevent heart attack and stroke Repairs damage to heart muscle Improves heart and brain energy production Protects the brain against disease (Alzheimer’s, Parkinson’s, Lou Gehrig’s) Can prevent viral damage to brain (i.e.:complications from mumps, measles) Combats migraine headaches.
No. 2: Idebenone
Idebenone is a synthetic form of CoQ10. Analysis has shown it to be as efficient at
producing cellular energy as CoQ10 itself. And it is a very powerful antioxidant as well. It is well absorbed and enters the brain in high concentrations, which is important. Analysis of people treated with idebenone found that its half-life is about 18 hours, which means
it is slowly removed from the body — and that is also key.
Idebenone also appears to possess significant antiinflammatory properties, and that puts it high on the list of supplements for use in preventing neurodegenerative diseases — especially Alzheimer’s and Parkinson’s. Remember, these ailments are
caused by chronic brain inflammation.
But idebenone has an additional benefit in treating neurological diseases — especially neurodegenerative conditions, strokes and brain injuries. It has been shown to significantly increase levels of nerve growth factor, a substance that promotes brain healing.
No. 3: The Carnitines
Like Co-enzyme Q10, acetyl-L-carnitine is naturally produced by the human body and is synthesized inside of us from the amino acids lysine and methionine. The brain, liver and kidney are the main manufacturing sites of acetyl-L-carnitine. Also, deficiency of lysine intake can lead to acetyl- L-carnitine deficiency. Both L-carnitine and acetyl-L-carnitine play an important role in the metabolism of fats by allowing them to be burned in the mitochondria, thereby releasing energy. Recent studies indicate they also play a role in energy production that occurs outside of fat metabolism.
Acetyl-L-carnitine differs from L-carnitine in that it can mimic acetylcholine the neurotransmitter responsible for muscle contraction and memory in addition to its many other functions. The carnitines enter the brain very easily, and another important property is their ability to stabilize cell membranes, making them soft (this reaction is called fluidity). One of the problems with aging is that the cell membranes get stiff and begin to function poorly.
Like idebenone, acetyl-L-carnitine can improve the function of nerve growth factor, which helps to repair the brain’s cells and connections (synapses). This can be especially important for people with disorders such as Alzheimer’s and Parkinson’s or brain injuries
and strokes. It has been documented that acetyl-L-carnitine can improve some of the cognitive problems associated with Alzheimer’s disease — including memory, personal care problems and depression. When combined with supplements like alphalipoic
acid, vitamins E and C, CoQ10 and multivitamins, the deterioration associated with
these diseases can be slowed. Better results would be expected with high doses of methylcobalamin (vitamin B12), vitamin B6, thiamine and folate. One of the more exciting combinations includes acetyl-L-carnitine and alpha-lipoic acid. Together, they have been shown to not only slow the aging of the brain they can reverse it as well.
But remember — it is important to keep in mind that anytime you increase energy production in the body (as carnitine and the other substances do), you also spur more free radical generation.
That’s why it is vital that you take your antioxidants either before or at the same time as you are taking these metabolic stimulants. This is probably why the combination of vitamin E and CoQ10 worked so effectively in aged mice.
In general, L-carnitine and acetyl-L-carnitine are well tolerated, even in high doses.
But of course, some people will experience mild stomach irritation with high doses (like 3,000 mg. a day). The acetyl-L-carnitine can cause agitation in higher doses, due to the acetylcholine produced. For this same reason, it can also worsen seizures for those
who suffer them. high doses of the acetyl-Lcarnitine can also cause muscle spasms and
twitching of the face and eyelids. If this happens, cut back on the dose or switch to L-carnitine. It is the acetylcholine produced by acetyl-L-carnitine that is responsible. L-carnitine does not create acetylcholine.
No. 4: Alpha-Lipoic Acid
This is another substance that is naturally found in the body. And like CoQ10 and L-carnitine, it is a powerful antioxidant that stimulates cells to produce more energy.
it lowers blood sugar, removes mercury, arsenic and cadmium from the body
(including the brain), increases the level of CoQ10 and glutathione in cells and controls the expression of some genes.
It’s also a powerful way to protect against radiation damage. In fact, because it was so effective, it was used to treat victims of the Chernobyl disaster in the Soviet Union during the 1980s. As if all this were not enough, it also directly blocks excitotoxicity in the brain.
Because of all these fantastic effects, alpha-lipoic acid when combined with other antioxidants and cell protectors greatly increases their effectiveness.
This has been proven in a number of studies, both in animals and humans. There are two forms of alpha-lipoic acid, an S-form and an R-form. The R-form is the most effective. Until
recently, only a mixed form of alpha-lipoic acid was available, which contained both S- and R-forms.
While alpha-lipoic acid is safe in even large doses, it does deplete the body’s store of biotin, an essential vitamin. This should be replaced using a multivitamin. The dose is 8 to 16 mg. a day.
For improving total and LDL cholesterol, studies have found benefit with beta-glucan at doses ranging from 3 to 15 grams daily. However, benefits have been seen more consistently at the higher end of this range, and one carefully designed study found no benefit at 3 grams daily
Beta-glucan products can contain molecules of various average lengths (molecular weight). Some manufacturers claim superior benefits with either high or low molecular weight versions. However, one study failed to find any difference between high molecular weight and low molecular weight beta-glucan for normalizing cholesterol and blood sugar levels.34
Beta-glucan, as a substance widely present in foods, is thought to have a high margin of safety. However, if it really does activate the immune system, harmful effects are at least theoretically possible in people with conditions where the immune system is overactive. These include multiple sclerosis, lupus, rheumatoid arthritis, asthma, inflammatory bowel disease, and hundreds of others conditions. In addition, people taking immunosuppressant drugs following organ transplantation surgery could, in theory, increase their risk of organ rejection. However, there are no reports as yet to indicate that any of these hypothetical problems have actually occurred. Maximum safe doses in young children, pregnant or nursing women, or people with severe liver or kidney disease have not been established.
You can take the top and best supplements in the world.
Should your operating program have any deficiencies, the supplements
may be of very little value.
Energy medicine, energy psychotherapy, guided imagery, mind spotting and hypnotherapy
will address most issues at all levels.
Reprogramming the sub-conscious is the most powerful method of achieving
ultimate health and wellness.
There is a fair amount of research on beta glucans and IP6 in Japan. Much of this came from the traditional use of mushrooms in oriental medicine (also how we got statins). But you've got an expensive list there, and the question would be, what are you trying to accomplish? As for effectiveness, as with medication, psychotherapy, guided imagery and everything else under the sun, everyone reacts differently, so no one can predict anything for a particular person, just tell you what traditional usage and research shows in a general way. Only experience will show you what works and what doesn't, and if you aren't currently suffering anything specific and are thinking of this prophylactically, you won't ever know if it helped or not. We are all an experiment, and most experiments end with ambivalence. If you're more specific about what you're trying to accomplish, we might be able to help more.