First, my long experience with this is that primary care physicians aren't the best people to do this with. You should have been directed first to a psychologist who specializes in anxiety treatment, and if no progress was being made your therapist would probably send you to a psychiatrist, the specialists in these medications. This is important because these meds can be very hard to stop taking to take correctly. Second, buspar doesn't really work very well by itself -- it's not done well in clinical trials -- but is tried often because it's easier to take and to quit taking than drugs that work much better. But it is often used after you start on an antidepressant and it's working but not working well enough. This is called augmentation, and your regular doc won't know much about it. Your dosage of Lexapro isn't enough to do anything, but this combination won't cause Serotonin Syndrome, which is very rare in any case. But I'd suggest seeing a therapist, because if that works you're cured. Drugs never cure, they just tamp down the symptoms, and they have side effects. But if you decide you do want to try meds, they aren't magic bullets -- they won't solve all your problems in life. They just make life easier. But you need ones that actually work, and for that psychiatrists are the ones who know these meds best, though that's no guarantee the first one you see will be a good one. Be persistent and do your homework and see if you can't figure this out with a therapist -- a short-term stay on antidepressants and anxiety meds doesn't always end up that way.