I have had anxiety off and on since 1999. I started Zoloft then and it worked the entire time I took it. I got divorced in 2003 and after several months of depression I started exercising, losing weight, and I felt better so I tapered off of it. I was drug free until last summer when I started having numbness in my face, dizzy spells, panic episodes, etc, I got a complete workup from my MD. All tests were negative so we decided it was my anxiety again so she started me on Xanax for short term. Over the last year, I have wanted to take something instead of the Xanax so I tried Zoloft again, Buspar, Lexapro, Paxil and ALL of them made my anxiety worse. Last week I saw my MD telling her that I have been depressed and I think the Xanax is doing it and the up and downs I am having all the time. She wanted me to start on Klonipin and I said NO WAY. She also suggested Biofeedback which my insurance does not cover and I cannot afford otherwise. I said no more benzos so I tried Effexor XR, I only took 37.5 mg yesterday and I was anxious all day, heart pounding, severe headache. I want to find something that works and I am at a loss, PLEASE HELP! Thanks