Hi. I have suffered from depression, off and on, since I was nine. I am a 54 year old woman. 13 years ago my oldest son was murdered, however I got through the investigation and subsequent trial with out having depression, outside of feeling horrible but considered it normal and situational. I believe that . At the time I was on 100 mg of Zoloft which I had been on for a few years. Three years ago, I had major surgery and now, have had 3 surgeries ( colon resection, umbilical hernia and recently my gall bladder was removed). About 6 months after the colon surgery, I began to experience horrible depression and anxiety. I have worked with my pdoc to get it under control but it has been frustrating. We have tried different drugs and I am now on Lamictal, Seraquel, Klonopin and Prozac ( we just titrated the Lexapro to add the Prozac). I thought I would be feeling better by now. I started on 20 mg. Prozac and was just ramped up to 40 mg, last week. I read on here about horrible withdrawal symptoms. By the way, I also am in therapy. Anyway, I am wondering if all of this is the withdrawal from the different drugs. When I have read on here about withdrawal symptoms I have not been sure if someone was just taken off a drug or switched like me. Finally, he has diagnosed me as bipolar 2. Before that , he would just say mood disorder comorbid anxiety. It is worse in the morning. I am also in pain management for the degenerative arthritis in my lower back so am on low dose percoset. I am prescribed 10 mg a day and split those into 4 doses during the day. Anyway, sorry this is so long but I would appreciate feed back especially from people who have gone through this or are going through this. Thanks and sorry this is so long.