Hello. I have panic disorder which slowly developed to agoraphobia. It all started when I entered puberty (14 years). I am now 24, with not psychological abnormalities what-so-ever, not even depression (certified by three different psychiatrists). My anxiety manifests itself without outside stimuli or emotional trouble. People with panic disorder and agoraphobia feel calm at home. From the moment I wake up in the morning, it feels as if I've been attached to an adrenaline IV. The moment my eyes open, my body feels as if it's been dipped into adrenaline - there are absolutely no outside stimuli (I just wake up!). It is so debilitating that I cannot stand noise or even function - again, from the second that I wake up. For 5 years I was on Lexapro and Klonopin, which really helped with anxiety, but never completely cured me.
I just recently had blood tests for thyroid which came back good. My question is - could I have a catecholamine problem?
I was put on Ixel, an SNRI, which absolutely unexpectedly removed my anxiety from scratch. My psychiatrist was amazed, since starting an SNRI usually gives extra anxiety. Sadly, it also made me more aggressive and my heart rate was 110bpm.
From what I've read so far, serotonin acts as a norepinephrine inhibitor, so that may be one of the reasons why it helped.
First off, do you think that a catecholamine imbalance can cause severe anxiety?
What blood tests would you suggest that I have done ? Are norepinephrine blood and urine tests accurate enough?
What are the possible treatments for excess norepinephrine?