The recommended daily maximum of Tylenol (acetaminophen) is 4000mg in a 24 hour period. There are many different factors to consider when determining if you have taken a dangerous amount of acetaminophen. People who are frequent alcohol drinkers may be at a higher risk for toxicity from an acute (one-time) acetaminophen overdose. Also, people who are malnourished or those with a recent period of fasting may be at an increased risk for toxicity.
Generally speaking a person who suspects an overdose of acetaminophen should consider the Emergency Department if they experience any signs or symptoms of toxicity, such as repeated vomiting, jaundice (yellowish tint of the skin), tenderness in the upper right part of your abdomen, or any mental changes. Adults should go to the Emergency Department after taking 7.5 to 10grams (10,000mg) of acetaminophen in a single period, or if they have taken more than 200mg per kilogram at one time. This can be determined by multiplying 200mg by your weight in kilograms.
If you have taken 7000mg of acetaminophen on other days, or if you frequently take 4000mg or more on a daily basis I would recommend you go to the Emergency Department as well, as this may also increase your risk of acetaminophen toxicity. Lastly, I would recommend if you have any feelings of poor health, or if you just 'don't feel well' and suspect you've taken too much acetaminophen, it is best to visit the Emergency Department to be on the safe side.They can take the necessary precautions to prevent any potential liver damage.
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