What you describe suggests that your son may have hypereosinophilic syndrome (HS). Elevation of the liver enzyme aspartate aminotransferase (AST) can occur in this condition, when there is heart involvement and can also be seen with muscular dystrophy (MD). However, with the normal AST range of 8 to 39, a value of 47 might still be in the normal or certainly near-normal range, especially considering elevations of several hundred in a number of disease states. In essence, please do not make too much of the AST of 47. Were the AST elevation due to MD, one would also expect an elevation of creatine phosphokinase (CPK), an enzyme that is contained in skeletal and cardiac muscle.
HS is a heterogeneous group of diseases. Therapy with corticosteroids is used for the treatment of most and additional therapy is available and dependent upon the type of HS. Newer medicines such as imatinib and mepolizumab are said to be promising. So, should your son have HS, there is reason to be optimistic regarding a positive response to currently available therapy.
You should request, of his doctor, an additional explanation for the tentative diagnosis of pre-hypertension.
Good luck.
Thank you for your thorough response. One item I failed to mention is that I have read Eosinophilia can be an indicator of Muscular Dystrophy. Please respond if you have knowledge of Eosinophilia being associated with certain types of Muscular Dystrophy. Last, the immunologist (Dr. Lierl of Cincinnati Children's Hospital) found allergy to mold and tree pollen although states that there are currently no allergens in the air that could be contributing to the Eosinophil level. I trust her opinion but am hoping for additional insight in regard to that area.
Thank you for your time and input.
Sincerely