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Can someone please explain what ANA 1:160 Centriole means?

Hi guys,

Got test results that say ANA positive 1:160, pattern: Centriole, and I'm wondering what that means?
My GP said it was a little out of his scope, so has referred me to a rheumatologist but the wait is quiet long.
I can see that it is thought to precede some diseases by 15 yrs or so - is this a "sure thing"? No family history that I can find.

In 28 yo male, uric acid also came back a bit high (0.46 mmol/L)- not sure if that


2 Responses
Avatar universal
Sorry, that was meant to say "(0.46mmol/L) - not sure if that makes a difference."

Also, if these are indicators of things to come, is there preventitive measures available?
1756321 tn?1547095325
A positive ANA (anti nuclear antibody) can be seen with various autoimmune diseases, as well as infections, cancer, lung diseases, gastrointestinal diseases, hormonal diseases, blood diseases, skin diseases, in elderly people, or people with a family history of rheumatic disease.

The centriole/centrosome proteins are found with Raynaud's phenomenon, scleroderma, Sjögren's syndrome, limited scleroderma (CREST), and viral infection.  

Hashimoto's thyroiditis (most common cause of hypothyroidism) occurs with increased frequency with certain immune diseases including scleroderma and Sjogren's syndrome. I mention this particular condition as it is one of the causes of high uric acid.

Causes of high uric acid include diuretic medications, excessive alcohol consumption, excessive caffeine consumption, family tendency (genetics), hodgkin's lymphoma, non-hodgkin's lymphoma, leukemia, hypothyroidism, niacin (vitamin B3), obesity, psoriasis, purine rich diet (organ meat, game meat, anchovies, herring, gravy, dried beans, dried peas and other foods), some immune suppressing drugs.
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