Thyroid peroxidase (TPO) is an enzyme in thyroid gland which helps in production of thyroid hormone. TPOab or antibody against this enzyme is present in cases where thyroid is attacked by body’s own immune system. Hence this is raised in autoimmune thyroid disease called Hasimotos thyroiditis. However, TPOab can also be raised in rheumatoid arthritis, Sjogren’s syndrome, lupus and pernicious anemia.Hence since you have other normal thyroid tests which happens in 10-15% cases of Hashimotos, other thyroid antibodies such as antithyroglobulin (anti-Tg), and to a lesser extent, TSH receptor-blocking antibodies, thyroid-stimulating antibody and cytotoxic antibody should be tested for. Also the tests should be repeated after 3 months. If these are raised then you may need treatment for thyroiditis. As of now you may not need treatment. Do discuss this with your doctor. Take care!
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