My daughter is 9 years old. She is a normal kid except she has been living with excruciating pain (mostly at night) for at least 8 years that can be calmed only by using ibuprofen. Before she could speak, I thought she might be lactose intolerant because of the way she would pull her legs to her belly and cry, but as she got older it became clear that it was joint or muscle pain. It is sporadic at times but recently became an every night thing. It first started with her waking me up around 3am crying in pain. She breaks into a sweat. If it's her ankle or knee that is causing pain - she can't walk due to weakness and can't even get out of bed or climb on the toilet. Sometimes she just lies on the floor and cries until it subsides enough for me to pick her up and hold her on my lap. If it is her shoulder, arm or wrist, she can't use her arm. Sometimes the pain can start somewhere and spread to another location in the same 'episode' (with more than one place hurting at a time). The pain lasts for about 20 minutes then subsides. It's just heartbreaking to hear her cry and ask why this has to happen to her and why does she have to have this pain!!! I have tried rubbing the location and using a heating pad to reduce the pain, but I don't think it does more than make her feel loved. I noticed that if she took ibuprofen at the onset of the pain, it would go away for the day, but if I didn't, the pain would come back within the hour - much worse. This could go on 3 or 4 times in a night leaving us both exhausted the next day. I haven't seen any signs of it happening after a day with more exercise or physical assertion than the next. I have even taken her to the ER in the middle of the night a couple of times but she's usually fine by the time we get there. Besides, they thought she was doing it for attention, however, a mother who KNOWS her child can usually figure it out - and when she wakes up out of a dead sleep crying and sweating and unable to walk, uh - she's NOT faking!!! After taking her to the doctors and to several specialists (rheumatologist, gastroenterologist) at Children's Hospital, we still have no explanation to what could be going on with her. She had an ultrasound of her abdomen back in '04, they did a CBC? and CMP? (normal), and has had several blood work-ups done including a test for Lyme's disease, the latest done last year.. I think the rheumatologist thinks I'm crazy because she seemed absolutely fine when I brought her in. When I had her in to see the rheumatologist, he said he didn't think it was arthritis because arthritis is usually only in the lower extremities. I told him that I was never sure whether she was going to wake up with pain in the middle of the night and I didn't like giving her ibuprofen on an empty stomach. It's very difficult to make a child who is crying in pain eat a cracker so she can take medication- especially because she is half asleep! On the other hand, if she had pain early in the evening and I gave her ibuprofen, she slept through the night. The rheumatologist told me to give her 1 ibuprofen before bed each night to resolve the issue. To me, this is just a band aid. I really feel something bigger is going on here. Am I supposed to give her ibuprofen for the rest of her life?! It's a nightmare if I forget to give her ibuprofen before bed...so I have to make sure even the babysitter knows the drill. One night she woke up with pain in her chest (last year) which spread to her shoulder. She laid on the floor crying, unable to get up and that scared me to death. Lately she has been waking up a few times a week, even though she has taken an ibuprofen before bed. It seems to be slowly increasing. Her urine is very pungent- just throwing that out there in case it's relevant. For the past few days she has been complaining of the left side of her rib cage tightening and hurting intermittently (maybe muscle spasms from exercise?) and headaches. The spasms in her chest were almost every five minutes on Saturday. Today is Wednesday and she’s only complained less and less each day since then. She’s been trying not to complain, but I can see her grab her side and wince every once in a while. I’m not sure if the increase in frequency of 'pain episodes' and these other symptoms mean anything, but I'm on my way to the pediatrician right after I'm done typing. I'm really hoping someone here can help me since the doctors haven't been able to! Thank you for any input you may have!