GP Notebook - Anti-smooth muscle antibodies -
"High titres are found in approximately 97% of autoimmune active hepatitis. Transient low titre antibodies may occur in other hepatic disorders, alopecia, primary pulmonary hypertension and in viral infections."
Low blood creatinine levels can mean lower muscle mass caused by a disease (eg: muscular dystrophy) or by aging. Other causes include severe liver disease, a diet very low in protein and water loss (pregnancy, excess water intake, and certain medications).
High MCH can be a sign of macrocytic anaemia (red blood cells are larger than normal. Enlarged blood cells are often associated with a deficiency or malabsorption of vitamin B12 and folate. Underlying causes can include liver problems, autoimmune diseases, severe hypothyroidism, bone-marrow diseases, use of certain medications and alcohol abuse.
I have malabsorption of vitamin B12 due to autoimmune pernicious anaemia and in my case my blood cells never enlarged even with B12 serum finally dropped below the reference range (a range that is far too low). I had plenty of neurological symptoms and I have permanent nerve damage.
Excerpt from MS Signs vs. Symptoms: What is the Babinski Sign?...
“Is MS the only disease which causes damage along the corticospinal tract? If I experience Babinski sign, does that mean I have MS?”
No. The abnormal Babinski reflex can be caused by several conditions including spinal cord injury or tumor, meningitis, stroke, amyotrophic lateral sclerosis (ALS), pernicious anemia, Friedreich’s ataxia, syringomyelia, poliomyelitis, rabies, brain tumor or head injury involving the corticospinal tract, or following a generalized tonic-clonic seizure."