Although I can’t comment directly on your diagnosis, you should be aware that most MS patients, and this is especially true for atypical MS (not meeting all of the clinical criteria for MS), and patients who have MS-like signs and symptoms have chronic infections that can also cause many other symptoms unrelated to MS. The most common infections found in MS patients include Chlamydia pneumoniae, Mycoplasma pneumoniae and other other species, Borrelia burgdorferi and other infections, including viral infections.
You might look into being tested for some of these infections, especially the ones mentioned above.
I have been diagnosed with MS since 2004. I have positive spinal tap with elevated wbc, and IgG and interestingly NO oligiconal bands which are seen in 95% of MS population. , MRIs have shown multiple enhanced lesions each time I have a relapse. I failed solumedrol (steroid induced psychosis). I've been on copaxone every day since 2004. I continue to have severe progression of many symptoms esp respiratory weakness, facial weakness, leg weakness. I failed tysabri; allergic reaction. I did 2 doses of novantrone 3 months apart but they won't let me try again because wbc went down to below 1.1. I do not tolerate interferon like avonex or betaseron due to very high fevers. Most docs now refer to my MS as progressive relapsing.
Meanwhile I am separately diagnosed with behcets disease due to apthous ulcers-non herpetic on eyes, inside mouth and 1 episode on genitals. i am on colchichine and plaquenil.
More recently, saw a new rheumy due to many new symptoms. ANA was 1:80 borderline positive nuceloated, and had antibodies + for scleroderma, have many areas of thickened skin on face, hands, also have severe episodes of reynaud's with changes in colors of fingers, white and blue, very sensitive to cold.; I have swelling of hands and feet, separately edema and now on lasix because got so bad. I have very dry eye and mouth; told sjogrens, had eye ducts cauterized..
Separatey I have vasculitis and hypercoagulation issues. i am on lovenox (not heparin) because still having heavy periods). I have very quick hypercoagulation problems and also factor 8 Leide n and factor V :leiden and anticardiolipin antibodies and antiphospholiopid syndrome. I am working with a MS neuro, a rheumy and a hepatologist/oncologist.
Still not getting any answers. and keep waiting for next doc appts,.
Separately, liver doc was watching high liver enzymes so removed gallbladder 4 weeks ago. Have very high Alkaline phosphotaste over 300 and GGT over 480 (and have never drank alcohol in life), and liver enzymes were still in the 100s. liver biopsy just showed fatty liver. He has run tests first ASMA and AMA were positive , then ASMA was borderline, and thinks i have AIH but not sure...he wants the rheumy to monitor me on imuran. (i can't take prednisone due to psychotic behavior when on prednisone/solumedrol)...What will it take for rheumy to confirm definitely sclerodoma. I also have issues related to sclerodoma affecting mixed connective tissue, sjogrens, polymyositis, and chronic reflux, neuropathy (but also have MS); also have extensive esophageous inflammation. Seems like each specialist I see the ywant me to see someone else.
I don't know if all of your problems are related, but in some patients essentially all of the multiple problems you listed were associated with chronic infections that invade many organs (vascular system, liver, thyroid, CNS, eyes, skin, etc.). In complex cases like this where multiple diagnoses are present, we always suggest that chronic infections be considered.