Your pain sounds like fibromyalgia, and you should look into this. So, what possible linkage could there be between progressive MS, asthma, COPD and fibromyalgia?
One possible link is that all of these conditions show a very high prevalence of chronic infections. Let’s just consider one type of chronic infection (Since I know quite a bit about this infection, I will use it as an example, but it is only one example of the type of chronic infection(s) that could be at the bottom of your problems). For example, if we consider positive systemic Mycoplasma infections, fibromyalgia (~70%), progressive MS (~50%), asthma (~40%), and COPD (% not established, but significant)—all of these conditions show some evidence of chronic infection(s).
In our experience all of the infection-positive chronic illness patients benefited from anti-infective therapies. Thus this is something that you should look into.
I forgot to mention that I have horrible pain in my legs every night when I lie down to watch tv. I was given Amytriptyline years ago for this pain but it is no longer working. Again, I thank you for any help you can give me!