Premerin contains only estrogen and is used primarily in the prevention and management of osteoporosis, vasomotor symptoms and vaginal dryness associated with menopause. Although the relationship between estrogen and autoimmune disorders is not clear, such hormones can stimulate some chronic infections. This may be why it can be associated with DILE (Drug Induced Lupus). The majority of Lupus patients have chronic infections. In one of our studies over 50% had systemic Mycoplasma species infections. This type of microorganism is stimulated by estrogen, so it might be a factor.
Thank you Dr. Nicholson. I am going to a new Rheumatologist in the morning and I will ask him about this. Can it be cured with an antibiotic? If so which one?