For some reason after taking Beta blockers, I actually get hypertension until around 24 hours after taking it, and then the hypotension Hits extremely hard. (Discontinued for this reason) Likewise for Northera, I actually get worsened hypotension, especially supine hypotension, until around the same time, although it seems to Not Change when going from laying to Standing. Why is this, rather than the normal quick responses to These meds? I'm 21 and have various Forms of dysautonomia, heart issues, anemia, and asthma.