Hi I was recently prescribed lithium for my bipolar depression and I was nervous about it at first. I have been on all kinds of antidepressants and mood stabilizers. I am currently on 300 mg twice a day, I am also on Lamictal which wasn't doing anything by itself. My only concern is that I also have Hypothyroidism with Hashimoto's, as well as narcolepsy with cataplexy. Does anyone know if my thyroid levels will level out over time and with my thyroid meds? Because I am "manic" right now I am all out of whack and I have lost 10-15 lbs and not sleeping. I have a mess of diagnosis along with a list of meds that keeps getting longer. I am on stimulants for my narcolepsy and I don't notice getting tired after taking lithium. I was told it doesn't take long to start working and to be honest I actually got up off the couch and cleaned my house today which I haven't done in more than 2-3 wks because of my depression. Any info that anyone has on my complex issues would be appreciated!! I will say I have found out a ton of info on lithium reading all the posts so thank you for the info!! I am hoping this works for me!!