I have been on the depo for 6 months, I gained 15 pounds as well (that was a plus for me) I was 120 lbs & now i’m 136 lbs. The 1st 3 month’s were not bad at all... My sex drive was high as hell, my periods stopped, & I was happy that I was gaining weight... HOWEVER, these last 3 months???? TRASH. I am stopping depo ASAP this was my last shot because my sex drive is completely gone. I am a college student and have been in a committed relationship for over a year. We went from having sex every other day to MAYBE once a month. Luckily, he is very understanding but this is taking a toll. I also have extreme discomfort, bloating and gas at night. It literally looks like i’m 4 months pregnant at night. My stomach gets so tight, that I was second guessing if I was pregnant. I have seen GI doctors and they said I do not have IBS, they aren’t sure what’s causing my discomfort and to change my diet. At that point, I knew it was the Depo. I told my gynecologist and it annoyed me that she immediately ruled out that it was the depo. Im like SIS I know my body very well. I have NEVER had any of these problems. I have always eaten a lot and I love to eat and cook a good meal... The only factor that has changed was me starting the depo. I still haven’t found a solution to my problems but hopefully my story can help someone else. Gas X temporarily helps with the discomfort but it’s annoying because I can still feel the fullness and gas but it takes away the pain associated with it. I just believe i’m too young to be experiencing these problems and obviously the depo has done A LOT to my body. I wish my gyno would have explained ALL of the potential risks. I did my own research prior but I could’ve never imagined my body would react like this.