I'm on the depo & I have just recently been put on Doxycycline 500mg. Twice a day. Does antibiotics lessen the effect of depo? What are the chances of getting pregnant while on antibiotics and taking depo?
Hi! If you were my patient, I would advise you that Doxycycline will not change the efficacy of Depo. If you are not overweight and if you do take your Depo on time, it should be 99+% effective. Of course you will want to use condoms to prevent STIs if you begin a new relationship. If you are using Doxycycline to help your acne, you may want to consider switching to oral contraceptive pills--they will often help your complexion. Good luck! Dr B
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