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Pituitary Problem?
Hello,
Obs: I write this originally in Portuguese and translated very quickly, I apologize for orthographic and grammar errors.
Could you help me with a pituitary problem? Is a lot of data.
She is a Brazilian, 40 years, works as a teacher.
About 5'4" and 98 kg. Actually I think is more water (swelling) than fat.
Symptoms:
- Sleep problem: She changes day/night periods, got better with Melanin but nowadays she wants to sleep all the day (sleepless and very tired).
- Eye problems: The vision has worsened, even with glasses.
- Swelling: Mainly legs and feet. She drinks a lot of water. When made the diabetes insipidus test. Was inconclusive...
- Memory problems: Some days she has problems with her short-term memories, acting dizzy.
- Bone problems: She have a bunion problem and this is getting worse, in fact look likes her feet are growing. She thinks the problem is just the bunion, but for me her feet are enormous. She used to wear 7,5 but now she need to buy 8,5 or even 9 shoes!
Besides this she has back pain and went to a doctor who says the cause is an extra bone in the spine, he said that this is not unusual. The problem is she was in a car accident with a neck injury, when she was 18. And then no one saw this extra bone.
-Liver: Her liver is not ok, have a serious steatosis and the numbers are Ferritin 147, Gama GT 44, TGO 66 and TGP 102.
- She always have bad numbers in prolactin, the last was 40.5. The doctors said that was a depression medicine issue. She has clinical depression (but stops the medicine, now uses Hypericum).
- The T4 levels are always close to the limit, yesterday the T4 free was 0.81. She uses levothyroxine sodium, 75mgc
Well, all point to Pituitary, right?
She had a RMI in 2013, they found a small cyst on the pituitary. All doctors said it is so small to damage the pituitary. But the symptoms were there. And nowadays all symptoms are worst. She repeated the RMI, the results are below.
Someone can explain what she has?
RM SADDLE / pituitary
RESONANCE SADDLE TURKISH
Method:
Examination with FSE sequences in T1 in the coronal and sagittal planes,
with 1.7 and 2.5 mm in width, after administration of
intravenous paramagnetic contrast (gadolinium).
Study supplemented with cuts in T2, the ESF sequence in the plan
coronal.
Held FLAIR sequence in the axial plane for further evaluation of
brain.
Analysis:
Seal cavity shape and dimensions preserved.
Compatible with a small cyst in protein content,
characterized by isosignal T1 and hypointense on T2 marked measuring
about 0.3 cm, interposed between the anterior and posterior lobes of
hypophysis.
Posterior lobe of topography and intensity of normal signal.
Pituitary stalk centered and preserved caliber.
Suprasellar cistern free.
Optic chiasm uncompressed signals.
Cavernous sinus and opaque with no apparent injury.
OPINION:
Findings consistent with small cyst pars intermedia, displaying high
protein content.
There were characterized changes to the inspection of a
11/07/2013.
Note: Rare hyperintense foci on FLAIR white matter
supratentorial, nonspecific. Small arachnoid cyst in the fossa
left middle cranial. Dig the persistence of the septum pellucidum and
vergae (anatomical variation).
Obs: I write this originally in Portuguese and translated very quickly, I apologize for orthographic and grammar errors.
Could you help me with a pituitary problem? Is a lot of data.
She is a Brazilian, 40 years, works as a teacher.
About 5'4" and 98 kg. Actually I think is more water (swelling) than fat.
Symptoms:
- Sleep problem: She changes day/night periods, got better with Melanin but nowadays she wants to sleep all the day (sleepless and very tired).
- Eye problems: The vision has worsened, even with glasses.
- Swelling: Mainly legs and feet. She drinks a lot of water. When made the diabetes insipidus test. Was inconclusive...
- Memory problems: Some days she has problems with her short-term memories, acting dizzy.
- Bone problems: She have a bunion problem and this is getting worse, in fact look likes her feet are growing. She thinks the problem is just the bunion, but for me her feet are enormous. She used to wear 7,5 but now she need to buy 8,5 or even 9 shoes!
Besides this she has back pain and went to a doctor who says the cause is an extra bone in the spine, he said that this is not unusual. The problem is she was in a car accident with a neck injury, when she was 18. And then no one saw this extra bone.
-Liver: Her liver is not ok, have a serious steatosis and the numbers are Ferritin 147, Gama GT 44, TGO 66 and TGP 102.
- She always have bad numbers in prolactin, the last was 40.5. The doctors said that was a depression medicine issue. She has clinical depression (but stops the medicine, now uses Hypericum).
- The T4 levels are always close to the limit, yesterday the T4 free was 0.81. She uses levothyroxine sodium, 75mgc
Well, all point to Pituitary, right?
She had a RMI in 2013, they found a small cyst on the pituitary. All doctors said it is so small to damage the pituitary. But the symptoms were there. And nowadays all symptoms are worst. She repeated the RMI, the results are below.
Someone can explain what she has?
RM SADDLE / pituitary
RESONANCE SADDLE TURKISH
Method:
Examination with FSE sequences in T1 in the coronal and sagittal planes,
with 1.7 and 2.5 mm in width, after administration of
intravenous paramagnetic contrast (gadolinium).
Study supplemented with cuts in T2, the ESF sequence in the plan
coronal.
Held FLAIR sequence in the axial plane for further evaluation of
brain.
Analysis:
Seal cavity shape and dimensions preserved.
Compatible with a small cyst in protein content,
characterized by isosignal T1 and hypointense on T2 marked measuring
about 0.3 cm, interposed between the anterior and posterior lobes of
hypophysis.
Posterior lobe of topography and intensity of normal signal.
Pituitary stalk centered and preserved caliber.
Suprasellar cistern free.
Optic chiasm uncompressed signals.
Cavernous sinus and opaque with no apparent injury.
OPINION:
Findings consistent with small cyst pars intermedia, displaying high
protein content.
There were characterized changes to the inspection of a
11/07/2013.
Note: Rare hyperintense foci on FLAIR white matter
supratentorial, nonspecific. Small arachnoid cyst in the fossa
left middle cranial. Dig the persistence of the septum pellucidum and
vergae (anatomical variation).
That is odd to not test for GH. There is also Cushing's syndrome - both disorders have a lot of similar symptoms.
Pituitary disorders can create a lot of symptoms that vary greatly. I had Cushing's and have low growth hormone.
Pituitary disorders can create a lot of symptoms that vary greatly. I had Cushing's and have low growth hormone.
Thank You for the reply.
She had a lot of tests, but, i don´t know why, never has been tested for GH.
Besides the grow of the bones(?) she has a lot of lack of GH, as grow of fat mass, high triglycerides, metabolic syndrome and glucose intolerance.
I never figured that, her GH production may have experienced high variations...
She had a lot of tests, but, i don´t know why, never has been tested for GH.
Besides the grow of the bones(?) she has a lot of lack of GH, as grow of fat mass, high triglycerides, metabolic syndrome and glucose intolerance.
I never figured that, her GH production may have experienced high variations...
I would guess she really does not have a cyst but an adenoma (tumor). I think your friend has acromegaly. She needs growth hormone tests and IGF-1.
Find a specialist.
The liver issues WILL interfere with testing. GH is given off by the pituitary and processed in the liver to become IGF-1. IGF-1 is what the body uses.
She has a very dangerous problem and needs a specialist endocrinologist to help her.
Find a specialist.
The liver issues WILL interfere with testing. GH is given off by the pituitary and processed in the liver to become IGF-1. IGF-1 is what the body uses.
She has a very dangerous problem and needs a specialist endocrinologist to help her.
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