The below is a clinical summary of my mother:
"Mother of two, with no family history, postmenopausal, 59 yrs old working lady, underwent BCS at Apollo Gleneagles Hospital, Kolkata on 9th December,2010. Histology revealed grade II squamous cell carcinoma, 3/49 nodes positive, 3.5 cm tumor size, triple negative,T2N1M0. She was seenat Tata Memorial Hospital , Mumbai and was advised adjuvant chemotherapy with FEC90 # 4 followed by Paclitaxel/Carboplatin # 4 followed by adjuvant radiation to breast.
She has now developed multiple lung metastasis, histology is metastatic squamous cell carcinoma, triple negative. She has now been planned and started on systemic chemotherapy with Taxotere/ Xeloda, She is Anthracyclin and Taxane resistant disease."
My questions are:
1. Since she has been Taxane resistant in the 1st cycle of chemo where she was given Paclitaxel, does it make sense to give her Docetaxel now?
2. If it doesnt make sense to give Taxane now, what other drug should be given?
3. After how many cycles can we expect to see any clear results on the tumour by doing a x-ray or ct scan?
A medical opinion would be greatly appreciated.
thank you and regards.