Hi I am a fellow traveler in a situation very similiar to Patrica M. I have been recently diagnosed with metastatic breast cancer which has compromised some bones in my spine, ribs, pelvis and shoulder. My oncologist has put me on Tamoxefin and like Patircia, I am in the clinical trial ( Denosumab/Zometa). Her posting and the responses were of special interest to me as it sparked some questions regarding my own treatment. Obviously, like Patrica I was perimenopausal (very low Estrogen - on the brink of menopause). I have not been given Lupron and plan to have a discussion with my oncolgist as to why. Does anyone know of any research that compares use of Tamoxefin alone vs. Tamoxefin with Lupron or the resasoning behind using one or the other approach? If Lupron shuts down ovaries, isn't that effectively putting a woman into menopause. If this is the case, is the Tamoxefin still effective?
I was also interested to note Patricia is having another PET scan. I am concerned about the monitoring of the progression (hopefully halting or dissapearance) of my cancer. I will be having bone survey's because of the trial but as I understand this offers little information regarding the progression of cancer. Are there certain tests I should be asking to have repeated? What is the time frame for such testing? I have already had a series of MRI's, a PET, Nuclear Bone Scan, and a baseline bone survey. I appreciate this site! Happy Holidays