My sister is suffering from breast cancer since 1996. It was operated and she underwent hormone therapy, radiation and chemo therapy. Cancer cells were slightly receptor positive (about 15%).
Bone metastasis were detected last July, 2001.
Initially, a hormone (tamoxifen) therapy was applied. My sister is 40 year of age and premenopausal. A befriended physician strongly recommended to support the hormone therapy with LR-HR analogs - this recommandation was supported in the literature which we consulted. However, the oncologist does not recommand the application of of LR-HR analogs. His argument is the probably occurrance of side effects like, e.g., depression and a general decrease in the quality of life. Furthermore, he states that the application of LR-HR analogs alongside tamoxifen may be done in Europe but not in the U.S.
I would be interested in learning about your opinion on the application of LR-HR analogs alongside tamoxifen in premenopausal patients suffering from breast cancer metastasis in the bones (columna vertebrae).
Thank you so much in advanced.