My sister had her right breast removed 2 months ago. Her pathological exam reveals ductal carcinoma with highly differential cell type. 0/11 lymph nodes were positive. Immunohistological markers are tested from two centers one results were ER+, PR+, Ki67+<2% and Cerb-B2++ and the other is ER(-), PR+++, Cerb-B2+++ and Ki67 (-). Does she need hermone therapy and chemo at all and what is the prognosis for her?