My mother, mother of two, with no family history, postmenopausal, 60 year old working lady discovered a lump on her right breast in October 2009. She underwent BCS at Apollo Gleneagles Hospital, Calcutta, India on 9th December, 2010. Histology revealed grade II squamous cell carcinoma, 3/49 nodes positive, 3.5 cm tumor size, triple negative,T2N1M0.
She was seen at Tata Memorial Hospital, Mumbai, India and was advised adjuvant chemotherapy with FEC90 # 4 followed by Paclitaxel / Carboplatin # 4 followed by adjuvant radiation to the breast (31 sittings).
Unfortunately she has now developed multiple lung metastasis, the histology being metastatic squamous cell carcinoma, triple negative. She has now been put on systemic chemotherapy with Taxotere / Xeloda.
Doctors’ reports state that hers is an Anthracyclin and Taxane resistant disease.
Is the treatment she is going through now the best advisable?
We have been told that squamous cell carcinoma of the breast being a very rare phenomena has no documented cases and thus no reference. What are the chances of survival in my mother’s case and would you advise any other treatment?