What next?

[tulips]

I have been undergoing a clin trial for metastatic breast cancer that consists of Taxol and Xeloda. I have had to come off the Xeloda because of liver toxicity. I have been responding to this regimen in that my tumor markers and tumor sizes are coming
down. However, I am now wondering where do I go from here. I am well aware of the prognosis of this disease and my docs have made it clear they are looking for remission. I, however, am looking for a cure. I am wondering if I should press for extreme chemo to achieve this. I am convinced that Lance Armstrong survived
because he was willing to submit himself to a bombardment of chemo, almost to the brink of death. I am not yet considering transplant because I read that studies show they are no more successful than standard chemo. Would you agree with that? However, I will go that route at some point if it is my last resort. What do you think? Should I press for aggressive chemo? Do you have other suggestions? Also, I have been looking into visiting The Cancer Treatment Centers of America (Zion, IL & Tulsa, OK) for a consultation. Does anyone have any information/feedback on this organization? Thanks so much.

[CCF-RN,MSN-rf]

Dear tulips:  In general, metastatic breast cancer is considered "incurable" but not "untreatable."  That's not to say that "cure" could not be acheived but it is unlikely according to standard research.  Testicular cancer is a different disease that is known to respond well to chemo - even when metastatic.  Taxol and Xeloda is aggressive chemo.  Even taxol alone is considered aggressive therapy.  One advantage of using single agent chemotherapy is that either it works or it doesn't, you have less toxicity, and you don't spend time wondering which agent is working if you get a response.  You are right in your assessment of bone marrow transplant - more chemo did not prove to be better.  I know women who are living WELL with stage IV disease.  If you decide to get a second opinion, know that there are multiple correct approaches to this.  It may help you, though to have these discussions so that you can make informed choices.

[GRsmom]

Dear Tulips,

I'm not in the medical profession, but I couldn't agree with you more about Lance Armstrong!  I thought his book was wonderful and it helped so much.  Stay strong and be aggressive (too bad that we have to be!) in getting the care you need and deserve.
Your name will be added to my prayer list.  Attitude means so much, good luck.