Dear arkshanthi, Many breast cancers, especially those diagnosed at an early stage, are hormonally responsive - meaning that their cells grow in the presence of the “female” hormones estrogen (“E”) and progesterone (“P”). Both are naturally manufactured by and circulate in the human body, although at amounts that decrease after menopause, and with increasing age. ER/PR status being negative means that the cells do not have estrogen or progesterone receptors on the cells, and would not be stimulated to grow by the presence of estrogen or progesterone. Because of this, hormone treatment to block or lower estrogen would not be used to treat or prevent this type of breast cancer (ER/PR negative). You may want to have a discussion with your oncologist about the follow-up plan now that you have completed your cancer treatment.