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Biopsy report


Got this report for a friend's mother - not sure what stage cancer does this suggest, a repeat is requested but no answer on whether this is bad or curable. Any inputs on what to expect next, how bad is this:

Test: Mediastinal and abdominal lymphadenopathy.


Primary fixation of material submitted for review is technically suboptimal.

The biopsy shows scattered large atypical cells amidst a background of small lymphocytes.

The large cells express OCT 2 & CD 20 and are immunonegative for CD30, CD15, CD 3 & Pax-5.

The background lymphocytes are B cells expressing CD 20.

CD 3 & CD 5 expressing 'T' cell rosettes are noted around large cells.

In situ hybridization for EBR is negative.


Biopsy for Para-aortic lymph node :-

Suggestive of nodular lymphocyte predominant Hodgkin's lymphoma.

A well fixed repeat biopsy is recommended for a definite diagnosis.

Note: The internal and external controls have been found to be satisfactory.
1 Responses
219241 tn?1413537765
It appears that the pathology specimen was not really a good one. They have information which suggests Hodgkin's Lymphoma, but they are requesting another biopsy with a better specimen to either rule it out or say it is Hodgkin's Lymphoma.

Hope for your friend's mother the next biopsy doesn't show Hodgkin's Lymphoma. It is a type of cancer.
I hope that information helps you.
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