Got this report for a friend's mother - not sure what stage cancer does this suggest, a repeat is requested but no answer on whether this is bad or curable. Any inputs on what to expect next, how bad is this:
Test: Mediastinal and abdominal lymphadenopathy.
Primary fixation of material submitted for review is technically suboptimal.
The biopsy shows scattered large atypical cells amidst a background of small lymphocytes.
The large cells express OCT 2 & CD 20 and are immunonegative for CD30, CD15, CD 3 & Pax-5.
The background lymphocytes are B cells expressing CD 20.
CD 3 & CD 5 expressing 'T' cell rosettes are noted around large cells.
In situ hybridization for EBR is negative.
Biopsy for Para-aortic lymph node :-
Suggestive of nodular lymphocyte predominant Hodgkin's lymphoma.
A well fixed repeat biopsy is recommended for a definite diagnosis.
Note: The internal and external controls have been found to be satisfactory.