I have had a persistently high white blood count. In September, I ended up in the hospital for chest pains (I am a heavy smoker). It was 17,000. Two months later I had my WBC checked again and it was at 12,000. I thought it was an infection from 2 months earlier when my chest was hurting, and thought everything was coming back to normal. Well it is once again 17,000. I had an HIV and hepatitis test done, both were negative. I don't feel like I have an infection. Maybe alittle fatigued at times. I know my neutrophils were at 92% and my B-lymphocytes were at 15%. Not sure what that means. Now they want to do a bone marrow biopsy. I really don't want to do this. Does this WBC really warrant enough to go through a biopsy or are they wanting to do it needlessly? What could an elevated WBC mean?