I am a 48 year old female. In 2005 I was diagnosed with polycystic ovarian syndrome and insulin resistance. I put on all sorts of weight, and was up to 205 pounds in May, 2012. My family doctor put me on metformin, which I took for years up until last June. In June, 2012, I began to experience diarrhea and abdominal pain. In July I saw my gastroenterologist. By then, I was down to 196 lbs. He did an upper endoscopy, a colonoscopy, and a CT scan of my abdomen, all of which came back negative. The gastroenterologist put me on Lomotil and Imodium for the diarrhea and it eventually subsided. I blamed the metformin for my diarrhea and asked my GP if I could go off it if I could get my insulin resistance under control with diet and exercise. He agreed.
In August, 2012 I started the South Beach Diet. I began to lose, on average, 12 pounds a month. In October I injured my foot and could no longer exercise, so I began to restrict my caloric intake to 600-750/800 calories a day. I ate fruits, vegetables, and whole grains. No sweets, little sugar, all very low glycemic index. I went off birth control pills and Zyprexa and lowered the amount of antidepressants I take per day.
Last week I had routine bloodwork done by my GP and my calcium came back at 10.8. My albumin was 4.7. My GP “corrected” my calcium to 10.2 and said it was normal. I am down to 129 pounds and still losing, even though I am trying to eat more. I have little appetite. I find that when I eat more I have diarrhea and feel guilty. I talked my GP into retesting my calcium and testing my PTH. My calcium was still 10.8 (high) and my PTH was 33.4.
Is the type of weight loss I have experienced normal given my diet, or should I be worried about cancer? What about hyperparathyroidism?