Cancer Community
6.56k Members
Avatar universal

?growth rate

can cancer of base of tounge grow from T1 to T4 in 45 days?.
i m dr.ajay from india .(radiologist)
1 Responses
Avatar universal
Hi.  What's the histology of that base-of-tongue cancer you're asking about?  If it's squamous cell carcinoma, some in vitro tongue SCC cell lines have doubling times between 28-40 hours, so it's theoretically possible for a T1 lesion (2 cm diameter or less) to progress to T3 (greater than 4 cm diameter) in less than 45 days.  T4 stage would involve not just an increase in size, but invasion of adjacent structures, like bone or extrinsic tongue muscles.  The propensity of the tumor to invade depends on its "aggressiveness", which can be estimated by looking at the histology.  That's why I asked about it.
Have an Answer?
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Here are 15 ways to help prevent lung cancer.
New cervical cancer screening guidelines change when and how women should be tested for the disease.
They got it all wrong: Why the PSA test is imperative for saving lives from prostate cancer
Everything you wanted to know about colonoscopy but were afraid to ask
A quick primer on the different ways breast cancer can be treated.
Get the facts about this disease that affects more than 240,000 men each year.