I was asked to post my information and video about Convenia here. This drug isn't safe due to how long it stays in the system alone. If your cat or dog has a bad reaction it will be very difficult to counteract that. I hope this will help someone avoid the death or harm of their beloved cat or dog. Please inform yourselves about Convenia if you're not familiar with and request that NO CONVENIA be put in the charts. Lets take this drug off the market for good..
My cat Angelina had a reaction to Convenia only 10 days before she passed away. I did a necropsy at Cornell Hospital Pathology Dept. They found that they think she had liver adenoma/ cholangiocarcinoma as well as acute myeloid leukemia. In spite of the fact that she had an end stage liver cancer, it seems, nothing to that effect showed up in her blood work until 4 days after the Convenia shot. At that point her AST was elevated but not tremendously and they thought she had an infection. 4 days after that she had become severely anemic, there was no sign of anemia in any of her blood work before this. She also had a 4 minute claw test, which means she took 4 minutes to stop bleeding.
The findings at Cornell said that they did not believe Convenia caused her anemia, not because it wasn't possible, but because Convenia hasn't been reported to cause anemia. This isn't true, read Dr. Pierson's website, read Pfizer's own foreign market results which state it has caused hemolytic anemia- I have also communicated with someone else whose cat developed hemolytic anemia and who passed away after 4 blood transfusions and I have read other accounts of anemic reactions. So this drug does cause anemia as well as many other severe effects.
When Angie received Convenia she had what seemed to be a cold which wasn't going away, she didn't seem gravely ill at that point. She had had some weight loss in July, but her blood work was normal. We did a thyroid panel in September which was fine. Then she had some hair loss for which I never found out the cause yet.
After Convenia, she developed a high fever, she became extremely doped, she was hiding in the closet and she stopped eating completely. Throughout this she kept seeming to revive as if her body was trying to fight off the reaction. She was given Orbax and her fever lowered and she ate three dishes of food, but then she regressed and started hiding again.. it was at this point I believe the anemia began... I had given her fluids at home and the next day when I brought her for an ultrasound of her abdomen, they thought from an xray that she had possible pancreatitis and had given her more meds for that, she had a large bruise at the site of the fluids.
That day her dvm told me she was severely anemic and she thought Angie was dying... the dvm was very upset- she was crying. I took Angie to a speciality hospital where she was given iv fluids, pain killers and tested. They told me that night they were considering Convenia as a cause of her anemia, I had just read all about it, not having been warned of any of the severe side effects, and I called them to tell them about that. I decided to take her home and try to treat both the cancer and the FeLV( see below) with steroids and other drugs, but I knew the next day she was in too much pain and I had to let her go.
Now that it has been determined that she had a non felv related cancer, as well as acute myeloid leukemia, which could or could not have been caused by FeLV, she had one inconclusive and one positive eliza test but no IFA test, which I was finally informed of the day she left the speciality hospital, I fear that both Pfizer and dvm societies will not believe that Convenia played a role in her death.
I still plan to file reports with Pfizer and with the FDA as well as warn everyone I can not to use Convenia. I will never use this drug again- I had already refused it once in July when Angie developed a cold after receiving two vaccinations. I had stopped vaccinating my cats due to health issues and I decided to do a rabies which I was still doing as well as a distemper. I think that was the trigger for her FeLV, assuming she really had this, because it stimulated her immune system too much. Angie was one of two kits of a feral queen who was put to sleep in a shelter, I believe that she may have contracted felv from her mom and then fought it off, but the virus hid in her bone marrow to later resurface.
I had never heard of Convenia before that but I rejected it on the basis that it stays in the system too long. I will always regret giving her Convenia, but had I been warned about the severe side effects reported in foreign market studies I NEVER would have allowed it. I think it is crazy that DVM aren't required to warn us about all of this. Please see my video Just Say NO to Convenia at youtube.
Please inform yourself because no one else is going to unless this drug is removed from the market, which is my goal. Don't risk the health and lives of your beloved fur babies. There are plenty of safe alternatives to Convenia. I would avoid Baytril also as I have read that it causes blindness and possibly other effects.
Please see my video "Just Say NO To Convenia" linked below for further information on how to treat an adverse Convenia reaction- aggressive probiotic therapy has been used successfully.
Here is a list of adverse reactions reported in the foreign market study conducted by Pfizer: Please report all adverse events to Pfizer and to the FDA. 1-800-366-5288
FOREIGN MARKET EXPERIENCE: The following adverse events were reported voluntarily during post-approval use of the product in dogs and cats in foreign markets:
death, tremors/ataxia, seizures, anaphylaxis, acute pulmonary edema, facial edema, injection site reactions (alopecia, scabs, necrosis, and erythema), hemolytic anemia, salivation, pruritus, lethargy, vomiting, diarrhea, and inappetance.
For a copy of the Material Safety Data Sheet (MSDS) or to report a suspected adverse reaction call Pfizer Animal Health at 1-800-366-5288.
"High doses of Cefovecin sodium (Convenia) can cause nephrotoxicity, neurotoxicity, hepatitis, changes in the blood leukogram and thrombocytopenia." *This is from Pfizer or another drug promoter's own literature- unfortunately for some cats and dogs this happens with one NORMAL dose.
Occasionally, cephalosporins and NSAIDs have been associated with myelotoxicity, thereby creating a toxic neutropenia4. Other hematological reactions seen with cephalosporins include neutropenia, anemia, hypoprothrombinemia, thrombocytopenia, prolonged prothrombin time (PT) and partial thromboplastin time (PTT), platelet dysfunction and transient increases in serum aminotransferases.