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Paranoid Schizophrenia cat

I have four cats. 1 male and 3 females. Male is the oldest. The oldest female has always been a little bit weird. We thought that maybe she just had a weird personality. I am the only one she comes to. Recently her behavior has been a little more odd. Its like she lives in an alternate reality. All the other cats get along really well. They all play together and sleep in the same area. She has never really been a fan of the other cats but has handled it well. I only got them as company for her because the male likes to go outside during the day. So she is paranoid all the time for no reason. Always running away. She constantly growls at the other cats like they are trying to get her. Sometimes one will be at the other end of the hall and if she walks towards it SHE growls. They are clearly not after her sleeping at the end of the hall. She also has mood changes. Sometimes she is very sweet and sometimes she acts as if there is something terrible trying to get her. I have had her since she was a kitten and never mistreated her. There is no abuse history that can be attached to this. I was there the day after she was born so I know what environment she was in before I got her. If she is mentally ill is there anything I can do to help her?
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Yes, she is an indoor cat. Her choice. Sometimes she will run outside while the male is coming in and out. She acts like she cant wait to be out there, but then she gets scared of everything and runs right back to the door within 30 seconds. We have a very large yard and the male has wanted to be outside from the beginning. I let the cats live their lives however they choose I just make it easier and more comfortable for them. I would never deny her outside if that is what she wanted. I just feel bad that she is always afraid inside or out.
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535822 tn?1443976780
Is she an indoor kitty , sometimes they want to be outside its not a normal environment for a cat living continuously in a house.I know many do okay but it can affect others ,I had a friend had 2 abbysiniums,(spelt wrong I bet,) their behavior in her house was crazy, they wouldn't come to you, they fought, leapt all over the place ,tried to get out of the door every chance they got. Again I am not saying all indoor cats are like this but maybe you have one would rather go in and out..
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