IgA is the antibody that protects your gastrointestinal tract and respiratory tract among other things.
In the medical setting I am in, we see elevated levels of IgA before someone turns up with either gluten-sensitivity or celiac disease. We tend to look at it as the body is in the initial stages of ramping up and fighting the incoming gluten - and it's doing a great job. But at some point it just isn't able to continue the 'fight' and the total levels of IgA plummet. Somewhere in there, we typically find that IgA-gliadin levels rise.
It can take many years for someone with celiac disease to actually 'show' damage in the duodenum that allows a doc to be suspicious and take biopsies that result in a diagnosis. In some cases, I've heard it takes up to 10 years. A lot could be going on during that time including the changes in IgA levels.
You might want to consider doing a gene test for gluten to see what genes you're carrying. It might give you an early idea of whether or not you're current elevated levels of IgA could be correlated with a diagnosis of celiac disease that may be made at a later date. Enterolab has a decent gene test. Take a look.
Thank you so much for responding. That does make a lot of sense. I have a question for you though.
Is it possible that maybe if I went gluten free now even though I didn't technically have to that it would give my system great re-leaf? And possibly greatly delay or possibly permanently delay anything worse from happening from continually eating gluten.
Basically could I lower my IGA levels back to a normal range by eating correctly and eliminating gluten out of my diet or is this impossible and my IGA level are going to stay where they are no matter what I do?
Thank you so much for your help and look forward to your answer.
Anyone have any new information on high level of IGA when everything else is perfectly normal?
The only way you'll know is to give GF a trial and see what happens. If you try GF and retest IgA levels in about 8 months to a year and see a difference, you'll have your answer.
It's not hard going GF, I did it only as a trial and then realized I felt better, seems I have been ill for a long time and did not know it. You don't need bread, but do take a good vitamin because you will need that. It took me 2 weeks before I felt really good. Gluten is in a lot of things, so read up.
Doctor says I cant lower my IGA levels, do you think that is false? I was thinking why couldn't I.
I agree. I might try that anyways and see if it helps me a lot.
Ok I am not sure if this helps or not, but I no longer have the weird feeling in my left torso, that is gone.
The only feeling that I have left is the weird sensation right on the left side of my nose and possibly sometimes below my left eye.
It comes and go.
If I put an eye patch on my left eye I do not feel the sensation. So I am thinking it is eye strain or that it is just pressure from the patch distracting the other sensation.
I just went for a walk and I really didn’t feel it. So I think it might only come when I look down at the computer screen or watch TV.
I mean how are you suppose to know when you need glasses? I mean I can still read the words but is it just harder for me to do so now?
I recently moved a very heavy flat screen and put it on my shoulder/back, have been studying a lot by looking down and on the computer, and have been watching TV until like 4 in the morning sometimes.
I think this might be related to my Shoulders or middle back or upper neck but I am not sure. Can a pinched nerve affect facial muscles?
PLEASE HELP ME ANY WAY THAT YOU CAN!
ONLY IGA does not indicate celiacs, you will need the others iga,igg,ige, and anti-gliadin, and anti-transglutiminase antibodies. there is also a difference between sensitivity and celiacs. you can get a genetic test done to see if you have the genes for sensitivity or celiacs.
iga LEVELS can be elevated when your fighting an infection, or a low level chronic one.
it doesnt appear you celiacs, you would have to have skin manifestation Dermatitis herpitformis, or gastrointestinal issues. if your tests have no anti-gliadin, anti-glutanimase,anti-endomysial, along with the other levels of IG. it seems from the gym you had pressure utacharia. yes please doa genee test. i
I’m back and I’m still here. However, I have some questions.
My Doctor said I was on the borderline now. So I pressed him harder and asked him what did he mean and he said since I am on the max level of 20 on my Gliadin Peptide Ab, IgA that I should go Gluten Free now. As all of you know this is a big life changing thing. No more bread, pizza, sub way sandwiches, pasty, Italian food, etc. etc. The list goes on forever. I know I can make adjustments and I am prepared to, however I want to make sure I am reading all this correctly.
I am just still unsure if I will have celiac or have it now just the precursor, or do I just have an insensitivity to gluten. Keep it light but I can manage it.
I am little confused.
Do I go gluten free because I will get Celiac Disease if I don’t?
1-Do I have Celiac Disease or not?
2-If I don’t, does it looking like I am getting it?
3-What should I do?
4-Can you be in between it? Meaning can I be sensitive to gluten but yet eat it a little bit in moderation?
5-If I went 1 year off gluten, repaired my bloodwork numbers, and had little bits of bread here and there with gluten would I be okay?
6-My dad had celiac or thinks that he does, he never officially did the biopsy, however, he had lying on the floor pain to where he wanted to kill himself. Now that he is gluten free he never has that pain again. I have never experienced anything close to this. Will I?
7-Am I missing anything else from these results, does high iga or Ab, iga mean anything else with no other symptoms?
I have ibs out bursts, low intestine problems for sure off and on. Headaches sometimes. I am thinking that if I go off gluten anyway I am probably going to feel 1000 percent better. So I am thinking about trying it anyway, however its not the end of the world and I could keep eating loads of gluten, if everything stayed the same. However, if this blood work looks like I am heading for a on the floor screaming in pain session later in life, I mine as well take care of it now.
All my other full comp labs came back normal besides my slightly high bad cholesterol.
PLEASE HELP ME BECAUSE I AM SO CONFUSED. ANYTHING YOU CAN DO WOULD BE GREATLY APPRECIATED. PLEASE SEE ALL MY RESULTS BELOW RELATING TO CELIAC.
History of results:
HDL Cholesterol = 32 L
Should be >39
IgA = 682 H / Should be 68 - 379
Endo = Negative
tTg Ab, IgA = 8.3 / Should be <20
Gliadin Peptide Ab, IgG = 9.2 / should be <20
Gliadin Peptide Ab, IgA = 10.0 / should be <20
tTG Ab, IgG = 6.5 / Should be <20
IgA = 608 / Should be 68 - 379
Endo = Negative
tTg Ab, IgA = 11.9 / Should be <20
Gliadin Peptide Ab, IgG = 9.7 / should be <20
Gliadin Peptide Ab, IgA = 12.1 / should be <20
tTG Ab, IgG = 10.1 / Should be <20
2014 – Different Test
CCP Antibodies IgG/IgA = 12 / should be 0 – 19
2014 – Different Test
Immunoglobulin A, Qn, Serum = 710 / should be 91 – 414
2014 – Different Test
Immunoglobulin A, Qn, Serum = 721 / should be 91 – 414
Immunoglobulin M, Qn, Serum = 271 / should be 40 - 230
2014 – Different Test [Later in the year]
Immunoglobulin A, Qn, Serum = 753 / should be 91 – 441
Immunoglobulin M, Qn, Serum = 270 / should be 40 – 230
Immunoglobulin A = 690 / should be 68 – 379
Endomysial Screen = Negative
tTG Ab, IgA = 2 / should be <4
Gliadin Peptide Ab, IgG = 2 / should be <20
Gliadin Peptide Ab, IgA = 20 / should be <20
tTG Ab, IgG = 1 / should be 40