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Has anyone had problems with Simvastatin or ezetimibe causing excessive fatigue?

StoneJExternal User
I have been taking Simvastatin on and off for years.  About two years ago my doctor added ezetimibe to my regimen.  It has been lowering my bad cholesterol how ever the first of this month I missed taking them for about a week and for the first time in years I felt less fatigued.  I do have Fibromyalgia which is usually the cause of my fatigue, but this is a different type of fatigue.  I have not restarted either of the cholesterol meds back because I have felt so much better.  I know I need to talk to my doctor about it.  I just wondered if anyone else has had this experience with either or both of these meds.
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15695260 tn?1549593113
Hi there and thanks for your question and joining the forum.  Please always check in with your doctor on these matters so they can guide you.  Unusual tiredness and weakness is listed as a 'less common' side effect of Simvastatin.   https://www.mayoclinic.org/drugs-supplements/simvastatin-oral-route/side-effects/drg-20069006.  For most people it doesn't cause significant issues, however.  With all medications, weighing risks and benefits to taking the medication must be done.  If a side effect impacts life too much, then it may be the case that it is better to give up the benefit it provides if taken.  In this case, keeping your cholesterol in check is the important factor.  If you aren't going to take the medication, please speak to your doctor. There are natural ways to work on lowering and maintaining proper cholesterol numbers.  Here is a list of natural ways https://www.webmd.com/cholesterol-management/features/11-tips-to-cut-your-cholesterol-fast#1

Watching your diet and exercising are going to be very important for you.  

Let us know how it is going!  
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