Hi, each individual may respond differently to this medication. It can cause headache, nausea, dry mouth, sweating, sleepiness or insomnia, and diarrhea or constipation and loss of libido. It can also cause increased or lowered blood pressure, sweating, anorexia, twitching and shock-like sensations. Also remember that as you lower the dose you are also lowering the side effects directly attributable to the medication. Regards.