I had a breast reduction and lift 4 years ago. I immediately contracted a staph infection in the hospital in my left breast which my surgeon believed caused fat necrosis. This large area has felt relatively rounded and smooth. 1 1/2 months ago I discovered a smaller, harder lump on this area. I went to my doctor and she scheduled me for a mammogram and ultrasound. Both of these came back suspicious, and they noted that the area in question (just under 1 cm)looks different from the larger fat necrosis area and is a solid mass. Also, 3 days before the mammogram I started getting an indentation in that area. I am scheduled for a biopsy in 1 week. My question is this - Could part of the fat necrosis area change after 4 years and look different? I have no immediate family history of breast cancer.