I have used Artefill in the glabellar folds for deep lines. This is an off label use since the filler is approved for only the nasolabial folds. On the few patients I have treated in that area, it appeared to work well. While expensive, the filler should be near permanent. If the problem is merely a result of muscle action, then it is unclear how well this will work. However, your problem seems to be present even without muscle action. This treatment should then be considered.
I have an extremely pronounced glabellar line (vertical line between eyes) - Grade 4. I tried Radiesse with Botox three times, lasted about 9 mos first time and only 2-3 months each time after that. We then tried Juvederm and botox which only lasted just over a month (and cost $1000). I'm an extremely active 37/m and my body seems to metabolize these fillers way too quickly. I'm interested in Artefill too. Anyone have any input if it works for glabellar?