Aa
Aa
A
A
A
Close
Avatar universal

Real talk about antidepressant weight gain

Has anyone ever been in my boat?  I have been on some antidepressant/SSRI or another relatively solidly for the past six years.  I have been on Zoloft, Paxil, Celexa and am currently on Effexor/Lithium w/Trazadone for sleep.  ALL of these drugs made me gain SIGNIFICANT amounts of weight.  Prozac and Serzone were weight neutral, but lost effectiveness or didn't work at all.  I started antidepressants, at 27, 5'7" and 125 lbs.  I am now 33 and weigh 178.
When I have gone off my meds in the past (I used to have a fantasy that I wouldn't need them forever.)or have been transitioning to a new one, I have lost SIGNIFICANT amounts of weight.  When I went off Paxil in 2003, I lost 30 pounds in 3 months (and no-- my eating/exercise didn't change).  I absolutely know that if I went off my meds right now, I'd lose a lot of weight in a short time.  I also know that a deeply debilitating depression would most likely follow at some time and that I'm probably "A Lifer" as far as depression treatment goes.
Yes.  I have had my TSH checked for thyroid problems.  My doctor will not prescribe Topamax because of the side effects.

I want to scream when I see websites that say just lower your calorie intake and exercise.  Yes I do that, but these medications absolutely do something to my body that no amount of diet and exercise seems to offset.  Yes!  That works for people not on antidepressants and even some who are, but not for everyone.  What about us?!!  As slender as I was, I could handle even a thirty pound weight gain, but at an extra 53 pounds, I feel huge, unattractive and though its really hard to exercise carrying all this extra weight around, I do.  I feel like I'm never going to date again.  I hate it!  Clothes never look right on me.  Adult onset diabetes also runs in my family, not to mention all the other health problems being overweight can bring.  For a long time I thought better to be bigger and emotionally healthy than skinny and sick.  But it's just gone so far and I just feel hopeless.  I think that if something doesn't change it's going to get harder and harder to exercise at all as I get heavier and heavier.

Is there anyone out there who was in a situation like mine, but then found the right medication, supplement, therapy, mindset or medication that actually allowed them to lose weight.  Is there some kind of special SSRI blend or new medication that I haven't tried that will stop me from putting on more and more pounds?  Please help!  I don't know what to do.  I need real help.  Something that works.
44 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Hi Andie,

That is great! I didnt mind Paxil except for the weight gain...and I could NOT lost it no matter what I did...

I think about this when I am exercising...because I hate exercising...this will allow me to live longer to be with my kids and family...so suck it up and keep going...and I repeat that over and over to myself...and after about 15 mins I actually feel better!!!

Have a great day!
Helpful - 0
Avatar universal
Hi Jogirl,

I really appreciate your comments!  As scared as I am about switching meds, I really want to try Welbutrin, although I know that though it worked for you, I still may gain weight.

While my appearance does effect me.  I don't enjoy looking like this.  I want to try to at least improve my chances of losing weight now before I get to the point of the person who had heart problems.  I want to deal with it now before it gets to that point.  And while I am motivated by appearance, I am even more motivated by health.  I am 20 pounds heavier than the healthy range for my height.  The even scarier thing is, I don't know if it will stop here.  I may continue to get larger and less healthy if I don't find a solution to this problem.
Helpful - 0
Avatar universal
Does welbutrin work for anxiety or just for depression?
Helpful - 0
Avatar universal
i can feel your pain, believe me...my weight shot up almost 30lbs in like 2 months..and i had no idea what was wrong with me..they tried all kinds of blood tests and determined that my thyroid was off..i couldnt stay on those meds because i couldnt sleep.. i started having all kinds of emotional problems, flipping out at people for no reason, crying, paranoid..all that good stuff that comes along with depression...i just didnt want to admit it was depression..so finally when i swallowed my pride and went to the dr she put me on wellbutrin...that was january i was at 195..and am down to 170 right now...granted i have changed my eating habits somewhat and i have started walking and working out at least 3xs a week. Have you ever tried wellbutrin?? I have done a total 180..i feel much better..and my confidence is back again..i would suggest trying the wellbutrin!

goodluck!!!
Helpful - 0
Avatar universal
i had slight anxiety..and that went away with the wellbutrin..everyone is different though..so all meds dont work the same for everyone
Helpful - 0
Avatar universal
Thanks Silver for another encouraging story.  After much discouragement, it's good to know that someone who had the same problems as me found what works for them.

Because I think I'm a depression treatment "lifer" if there's something out there that can diminish my weight gain problem, I think I need to try it after school gets out in a few weeks as long as my psychiatrist agrees.  And if Wellbutrin isn't it for me, maybe something else will be.  I'd love to hear other post-SSRI weight loss AND mental health stories
Helpful - 0

You are reading content posted in the Depression/Mental Health Forum

Popular Resources
15 signs that it’s more than just the blues
Can depression and anxiety cause heart disease? Get the facts in this Missouri Medicine report.
Simple, drug-free tips to banish the blues.
A guide to 10 common phobias.
Are there grounds to recommend coffee consumption? Recent studies perk interest.
For many, mental health care is prohibitively expensive. Dr. Rebecca Resnik provides a guide on how to find free or reduced-fee treatment in your area