I took Zoloft 75 mg for about six years for significant anxiety. It worked great for me. I had no side effects and was back to my cheery normal self. About four months ago, I decided to wean myself off because we are trying to start a family. I felt no difference on 50 mg or 25 mg. Then I dropped off completely and, four days later, started feeling really antsy. This has evolved until I was having full-blown anxiety again. I started back on the Zoloft after having been off of it for two weeks and that seemed to cause even more anxiety. Now I feel so hopeless, scared I am going insane as I can't seem to find the things that generally calm me or bring focus and purpose back to my life. It got so bad that all I do is worry, it never leaves me because I am soooo scared that the zoloft will not work a second time and that I'll never go back to the happy and completely content person I was just two weeks ago. I am afraid of going places as I had anxiety attacks yesterday at my facial which is usually so relaxing. It scares me even more because going places used to bring me comfort in times of anxiety and now I'm afraid I'll never be normal again. My doctor now also put me on lorazepam for a few days as I am building up on the zoloft. My question is, does this happen sometimes going off of the zoloft? Will it work the second time? My counselor, who is on vacation right now, said there is no reason to believe that the zoloft will not work again. All I know is that I feel so helpless and just want it to get better. I know I can hang in there if the zoloft starts working soon, but every day right now is such an agony. I do not know what to do, to start, where to go, how to help myself. Everybody, my husband, my parens, my counselor, they all say if it worked the first time it will work again. Is that true in your experience also? I responded really quickly to the medication last time. Will it take longer this time around? I just want to go back to loving food like I used to (everything tastes like paper now and I have to force myself to eat), being happy and content like I was just two weeks ago. Will I get there again? Thank you so much for your answer!!