In 2000, I overdosed on meth. I IMMED. began having severe panic attacks. I believe my situation is different-I don't have panic attacks because I have "unresolved issues"-it's due to the damage from the O.D. I have been on Serzone and Xanax for two years. They have helped somewhat. Recently, I began having severe abdominal pain. I took Demerol, had severe panic attacks , thus switched my med.'s to Klonopin. Dr. said Klonopin was a better drug to be on. I tried Zoloft, to replace the Serzone, but it increased the anxiety. I'm not taking anything to replace the Serzone or Zoloft at this time. I have had endoscopy, CT scan, blood work, etc.--all normal. I was treated for Heliobacteria and blood in stool. Could this be due to a physical problem or is it the anxiety? I have also had upper chest pain and very high blood pressure (220/121) and 127 heart rate since changing med.'s. I've also had EKG's-all normal. Could it be possible that I've had a stroke or other brain damage due to the O.D.? Could these symptoms I'm now having be due to withdrawal from Xanax. I abruptly stopped and substituted Klonopin-Dr. ordered. The Klonopin does not help with the blood pressure, but Xanax did. Also, I'm not taking a SSRI anymore. Could the Klonopin seem to not be working because of this? Where do I go from here? Are there any tests I should take re: possible brain damage? The blood press. has to be dealt with ASAP. What recommendations do you have? Re: the other physical symptoms I'm experiencing (shortness of breath, chest pain, weakness, abdom. pain, confusion, etc.) could this be due to w/drawals, lack of a SSRI, or just the anxiety? How do I respond to this? What is my best course of action. Please help!!!!!