My friend was diagnosed with bipolar disorder last year where
he had treatment in a hospital and continued taking Zyprexa.
He responded well then, overcame his delusions, but was not
entirely happy with his meds. He stopped taking meds early this
year and was very happy and did very well.
Last month he had another psychotic experience and had to be
hospitalized. This time he was put on Zyprexa and then changed
to Risperdal. Ten days in hospital and two weeks of day-visits for therapy later, when he went back to work,
he again did not do well (though he was taking his meds).
His doctor said that he may not be responding to Risperdal and
switched him immediately to Zyprexa (10mg/day).
He did not do well in the next three days and went back again
to the hospital.
He is now recovering in the hospital but his progress seems slow.
He seems sleepy all the time, and is on Zyprexa.
The hospital doctor now wants him to switch to Risperdal!
(It's been 1 week since he has been hospitalized.)
From what the doctors say, there is no clear reason for his
latest relapse. Two possible reasons are that he may not have
responded well to Risperdal, and that he may have gone back
to work too fast. Given that, it does not make sense to me
that he should be put back on Risperdal (presumably just because
he hasn't improved as fast as before and because he is sleepy).
What should we do?
We are planning to get a second opinion.
The other options are to change the doctor who attends to him
at the hospital.
We plan to follow this, but really, are we correct in doing so?
Also, is there any other reason why Risperdal can be better
than Zyprexa? (he may have bipolar disorder or may have
schizo-affective disorder of bipolar type).
Is it possible that some people simply don't respond to
a particular medication in the long run, but respond to it
in the beginning?
Any light on what may be happening, or what we should do will