second time on wellbutrin

[GatorGrl98]

Can Wellbutrin XL have a different affect the second time you take it? I was on it for about a year 3 years ago. I loved it! The only side effects were dry mouth and weight loss(not a negative). About 5 months ago my doctor put me on citalopram which made me feel like a zombie and I started gaining weight so we decided to switch to the wellbutrin. I have been on the wellbutrin for about 7 weeks now and off the citalopram for a little over 1 week. Im having a completely different experience than I did before. No dry mouth or weight loss instead headaches, ringing in my ears, clenched jaw, continued weight gain and irritability. Is this a different reaction to the wellbutrin or due to the combination of the two drugs? The headaches are more recent so I figured they may be withdrawal from the citalopram. I will be really disappointed if the wellbutrin doesn't work this time!

[Paxiled]

You'll probably have to ask this in a new thread, he doesn't usually answer a question in the middle of one.

[GatorGrl98]

I weaned myself off over 4 weeks. It's now been 4 weeks since I took my last citalopram and nothing has changed. How long can the side effects from the citalopram affect the Wellbutrin?

[Roger Gould, M.D.]

Your symptoms sound like the withdrawal effects  are masking the positive effects of the wellbutrin...did you wean yourself slowly or just stop...if you just stopped, you might go back on small dose for a week, then wean yourself over next two weeks, every other day for week two, and every third week for week three.