Depression Community
10.5k Members
Avatar universal

Cymbalta: Please tell me about your experience

Hi - I've been on Cymbalta for more than three weeks now and wondering how long it takes for mood to improve. I think I'm calmer but very blah and still quite depressed. I posted a couple of times and heard nothing. I don't know what to do. Afraid of what i've read here about withdrawal so going to keep at it and hope i feel better. But it would help to know how long it took for others.
5 Responses
Avatar universal
Can you say what dose your taking? It might be time to increase it. I took Cymbalta myself for a short time, two months. It was just too stimulating for me. We're all so different and react differently to the same med. If the increase does'nt help them you might want to consider trying something else.
433485 tn?1321816990
Hi.  I was placed on Cymbalta about a year and a half ago.  however, I had to go off after about a month due to horrible nausea that wouldnt quit and it dropping my blood pressure to the point that I almost passed out a couple of times. ( My bp is always in the normal range, as a matter of fact, they always point out that it is textbook perfect).  However, my younger sister has been on it for years and does great.  We are all different.  I would talk to your pdoc.
Avatar universal
Ive been on it only 1.5 weeks so no difference yet...It *****. I feel your pain.
Avatar universal
OK, three weeks and you feel calmer, that is a very good sign that it is working for you.

With that calmer feeling go forward , by 8 weeks you will start to smile and laugh and by 3 months you will feel very good.

It has been great for me, I feel so normal on it. I was on 60 mg, but for the last 6 months 30 mg, has done me fine, I dont have any drowsiness on 30.
Take time and be good to yourself.  After a while you wont be thinking about this and that is how you know it is really working !

Avatar universal
WARNING !!  I became absolutely suicidal on Cymbalta. Never has this been an issue for me.  Check out Cymbalta Forums and read what others have written.  Gather information to make an informed decision.   It works wonders for some and I am very happy that it does.  If you are not doing better in a week, see your doctor.  This drug is VERY, VERY difficult to get off of.  That alone, would make someone suicidal.  It took two months to wean off of it.  Literally:  Opened capsule and removed TWO GRANULES a day for 3 days, then spent the next three days removing FOUR granules, etc until gone.  Start another med while doing this so you don't spin out of control.  Then it has to work itself out of your system.  There are side effects but please know they will go away.
I envy those it works for and hope it does work for you, but do not wait much longer before contacting your doctor if your thoughts are becomming more negative.    
Have an Answer?
Top Mood Disorders Answerers
Avatar universal
Arlington, VA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
15 signs that it’s more than just the blues
Discover the common symptoms of and treatment options for depression.
We've got five strategies to foster happiness in your everyday life.
Don’t let the winter chill send your smile into deep hibernation. Try these 10 mood-boosting tips to get your happy back
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Here’s how your baby’s growing in your body each week.