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Imipramine withdrawal

My 23 year son has been taking Imipramine and Depekote for many years for anxiety and ADD.  He's attempting to ween off.   He did well with the Depakote decrease - down to half the dose after 3 wks.   Now decreasing dosages of both, he is experiencing severe withdrawal symptoms relative to the Imipramine even though following doc's instructions to halve the dosage.  How can he decrease those awful effects- skin crawling, startled feeling, weakness etc.  I'm very concerned for him.   (also feeling very responsible & guilty as the Mom!).  Any advice would be welcome.
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