Pristiq , Wellbutrin or Cymbalta for bad depression?

[thirdeye33]

Following a bad car accident, I have been dealing w/ terrible anxiety and ptsd. Besides my pain med and muscle relaxer, I take Klonopin 3 mg day. I have an appt. set w/ my reg. doctor to go over how bad my depression is. Most my depression I know stems from being extremely active and now 9 months later dealing w/ a terrible back/neck injury and pain and I can't be physical. My motivation is 0!! I go to all my PT appts and Chiropractor, etc. It feels hopeless....It may seem stupid, but ski season is coming up and now I was thinking this will be the first time in 15 yrs. I prob. won't be going. I just want to stand for 20 min. w/o pain in my upper back/neck. I'm beyond frustrated!!!
Anyway, the question?? A big question I have is feeling worse? Weight gain?(since I can't workout,might seem vain...but it will only depress me more) How long it takes to kick in? Mixing w/ Klonopin? I understand these our real ? for my doctor and everyone is different...just wanted some feedback.

Thanks in advance

[Tired55]

Hi there, glad to hear from you. No rush to send an inbox, and it doesn't matter where you begin, we can sort it out. I'm really sorry it's so hard to talk about, but maybe that's what you need. to get it out and let it go if you can. I know I asked a lot of questions, but just wondering how to help. Anything you can tell me would be a jumping off point, maybe just one thing... or, just take your time, as I said, no rush,whenever you fell comfortable to talk, I will be here to listen. It is a busy, crazy time of year if you let it get to you, just concentrate on getting better and hopefully the rest will fall into place. I realize that the Dr. won't usually increase your dose until you have been on the Wellbutrin for at least 8 wks., and think that is the most common dosage(150 mg.), that's how much I am on. Is it the XL? Hang in there and write when you can, no pressure. Tired55

[thirdeye33]

Thanks so much for offering to be a listener. I will send you an inbox as soon as I can figure out where to begin. It's just hard to talk about.

[birdie0907]

I doubt your dose will be increased unless you start to get some positive effect from it. I was told W can take 8 weeks for the full effect, so I imagine doc will be reluctant to increase the dose in your trial period.

[thirdeye33]

Been on the generic Wellbutrin 150mg for 9 days.......any idea how long these things take? I'm in a downward spiral....my doc said this is quick acting one, she said should feel it within a week.

[John_jb1]

I used to take Cymbalta (Duloxetine) for sleeping problems associated with depression; Cymbalta should never be given to people with anxiety! As that would just make the anxiety worse... the same reason why people with mania such as Bipolar sufferers shouldn't take the stuff.

Also, I struggled to hell with the side effects of Cymbalta! Coming off of the stuff took me MONTHS - though that is an extreme example, apparently most don't get such issues.

So my advice (as not knowing much about the others) is don't go with Cymbalta...

Cheers,

- John -

[thirdeye33]

Thank you. I have my appt. with my Dr. next Thursday, Wellbutrin was what I was leaning towards. Feeling tired all the time is also a big problem..thanks for adding that in.

Take care

[Tired55]

  Hi there, so sorry to hear of your troubles. I can emphathize and sympathize with your situation, been there for a long time. If you are worried about gaining weight I would pick Wellbutrin as it is not known to cause weight gain,also won't make you as tired as some other antidepressants. Don't know about how it will react with your Klonopin though,good question for your Dr. or pharmacist. Hope this might help a little.  Good Luck, Tired55